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Ready for Fast Absorption

Experience spontaneous intimacy with HEZKUE®/BANDOL®. Fast absorption after just 5 minutes compared to Viagra® tablets2*

*Data based on mean plasma concentration after application of 8 pumps of HEZKUE®/BANDOL® (100 mg of sildenafil) compared to Viagra® tablets (100 mg sildenafil). Initial absorption of HEZKUE®/BANDOL® (100 mg of sildenafil) was observed within 5 minutes after administration (0.615 ng/mL, p = 0.012) vs Viagra® 100 mg tablets that showed no absorption at that time.

Ready for Fast Absorption

Experience spontaneous intimacy with HEZKUE®/BANDOL®. Fast absorption after just 5 minutes compared to Viagra® tablets2*

*Data based on mean plasma concentration after application of 8 pumps of HEZKUE®/BANDOL® (100 mg of sildenafil) compared to Viagra® tablets (100 mg sildenafil). Initial absorption of HEZKUE®/BANDOL® (100 mg of sildenafil) was observed within 5 minutes after administration (0.615 ng/mL, p = 0.012) vs Viagra® 100 mg tablets that showed no absorption at that time.

Ready for Innovation

With personalized dosing, HEZKUE®/BANDOL® is tailored to the users’ individual needs and lifestlyes and eliminates the need for planning.2
bottle icon - a discreet easy-to carry container

A discreet easy-to carry container2

Water droplet icon - no water required

No water required1

Leaf icon - refreshing min flavour

Refreshing mint flavour1

Ready for Efficacy & Safety

HEZKUE®/BANDOL® is bioequivalent to Viagra® tablets, offering a safe and effective alternative for treating ED.2
Ribbon icon - delivers the same efficacious dose as Viagra

Delivers the same efficacious dose as Viagra®2*

Graph icon - showed significantly better PK parameters

Showed significantly better PK parameters2

shield icon - has consistent safety profile

Has consistent
safety profile2**

*Compared to Viagra® 100 mg tablets and well-established safety profile for sildenafil used in the treatment of ED. ** With respect to AUC, measured after application of 8 pumps of HEZKUE®/BANDOL® (100 mg of sildenafil) compared to Viagra® tablets (100 mg sildenafil).

Ready for Innovation

With personalized dosing, HEZKUE®/BANDOL® is tailored to the users’ individual needs and lifestlyes and eliminates the need for planning.2
bottle icon - a discreet easy-to carry container

A discreet easy-to carry container2

Water droplet icon - no water required

No water required1

Leaf icon - refreshing min flavour

Refreshing mint flavour1

Ready for Efficacy & Safety

HEZKUE®/BANDOL® is bioequivalent to Viagra® tablets, offering a safe and effective alternative for treating ED.2
Ribbon icon - delivers the same efficacious dose as Viagra

Delivers the same efficacious dose as Viagra®2*

Graph icon - showed significantly better PK parameters

Showed significantly better PK parameters2

shield icon - has consistent safety profile

Has consistent
safety profile2**

*Compared to Viagra® 100 mg tablets and well-established safety profile for sildenafil used in the treatment of ED. ** With respect to AUC, measured after application of 8 pumps of HEZKUE®/BANDOL® (100 mg of sildenafil) compared to Viagra® tablets (100 mg sildenafil).

CLINICALLY PROVEN

Faster Absorption vs Tablets1

Extracted from Kaplan SA, et al. 2024.
#Data based on mean plasma concentration after application of 8 pumps of HEZKUE®/BANDOL® (100 mg of sildenafil) compared to Viagra® tablets (100 mg sildenafil). Initial absorption of HEZKUE®/BANDOL® (100 mg of sildenafil) was observed within 5 minutes after administration (0.615 ng/mL) while Viagra® 100 mg tablets showed no absorption at that time.
Viagra® (sildenafil) is a drug marketed in Spain by Viatris Pharmaceuticals S.L. (https://cima.aemps.es/cima/pdfs/es/ft/98077010/FT_98077010.html.pdf)

Initial absorption of HEZKUE®/BANDOL® was observed within 5 minutes after administration while Viagra® tablets showed no absorption at that time.1
HIGHLIGHTS FROM RECENT STUDIES

PHARMACOKINETIC STUDY2

Prospective, open-label, single-centre, two-way crossover comparative bioavailability study in 56 healthy male volunteers in fasting conditions.

HEZKUE®/BANDOL® is bioequivalent
to sildenafil tablets*2

HEZKUE®/BANDOL® is a safe and effective alternative for ED2

*The Pharmacokinetic study showed that HEZKUE®/BANDOL® was found bioequivalent to Viagra® tablet with respect to sildenafil systemic exposure, as reflected in the 90% confidence intervals for AUClast and AUC. HEZKUE®/BANDOL® and Viagra® tablet were not bioequivalent with respect to Cmax, with a modestly higher maximum sildenafil concentration for HEZKUE®/BANDOL®.1

UNICO STUDY3

Perception of Urologists and Andrologists in Spain about the Use of Sildenafil Oral Suspension in Patients with Erectile Dysfunction3
ADDITIONAL HEALTH EFFECTS

Erectile Dysfunction can be a sentinel symptom that effects other important aspects of your health

heart rate icon - High Blood Pressure & Obesity

High Blood Pressure & Obesity4

Elder icon - Comorbidity & Aging

Comorbidity & Aging4

pill icon - Anti-Anxiety Medications, Anti-Depressants & Sleeping Pills

Anti-Anxiety Medications, Anti-Depressants & Sleeping Pills5

brain icon - In young men, it is usually undervalued and attributed to psychological problems

In young men, it is usually undervalued and attributed to psychological problems6

References:

  1. HEZKUE®/BANDOL® is a ready-to-use sildenafil suspension spray. See HEZKUE®/BANDOL® product information (as of May 2024).
  2. Kaplan SA, Moore J, Niecestro R. Int J Sci Res. 2024;13(6):759-764.
  3. Peinado Ibarra F, García Gómez B, Luján Marco S, Segura Paños AM. Study UNICO: Perception of Urologists and Andrologists, in Spain, about the Use of Sildenail Oral Suspension in Patients with Erectile Dysfunction. Arch Esp Urol. 2023;76(2):139-44.
  4. Prieto-Castro R, Puigvert-Castro R, Artigas-Feliu R, et al. Opinions, Attitudes, and Perceptions in Relation to Erectile Dysfunction and Premature Ejaculation in the Undiagnosed Spanish Male Population. Results of the PANDORA Project. J Sex Med. 2020;17(8):1495-508.
  5. Martin-Morales A, Sánchez-Cruz JJ, Sánez de Tejada I, Rodriguez-Vela L, Jiménez-Cruz JF, Burgos-Rodriguez R. Prevalence and independent risk factors for erectile dysfunction in Span: results of the Epidemiologia de la Disfunction Erectil Masculina Study. J Urol. 2001;166(2):569-74. discussion 574-5.
  6. Rastrelli G, Maggi M. Erectile dysfunction in fit and healthy young men: psychological or pathological? Transl Androl Urol. 2017;6(1):79-70.
ADDITIONAL PRODUCTS

Next Products Coming to Market

Aspargo Labs is in the process of bringing the most important Rx and OTC medicines to market as oral suspensions.

Quotes from Key Opinion Leaders
Jesse Ory, MD Clinical Instructor and Urologist at the University of Miami
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“The nice thing with this is you can titrate up pretty easily without having to break up a bunch of pills and try and be your own pharmacist."

"The problem is there’s so there hasn’t been anything new, really, in ED for at least 10, 20 years, ...truly new that that is being used by everyone...but guys are going out and just getting anything they can that is different.”

Hossein Mirheydar, MDUrologist in Baldwin Park, California Kaiser Permanente
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“I think this product definitely looks like an exciting opportunity, in terms of the rapid onset of activity and also the utilization of a non-oral, GI-absorbing treatment. That’s definitely innovative. I would invite all my patients of all ages, to try an oral spray Sildenafil.”
Dr. Laurence A. Levine, MDProfessor of Urology Department of Urology at Rush University Medical Center, Chicago
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“I think in general the concept of something oral … that you can just simply spray in your mouth really easily, and don’t have to worry about a pill and all the rest, I think is attractive.”
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